Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease
نویسندگان
چکیده
Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease (PDD), an unexplained fatal inflammatory central, autonomic, and peripheral nervous system disease, showed 2 strains of a novel Borna virus. Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds.
منابع مشابه
Avian bornavirus associated with fatal disease in psittacine birds.
Thanks to new technologies which enable rapid and unbiased screening for viral nucleic acids in clinical specimens, an impressive number of previously unknown viruses have recently been discovered. Two research groups independently identified a novel negative-strand RNA virus, now designated avian bornavirus (ABV), in parrots with proventricular dilatation disease (PDD), a severe lymphoplasmacy...
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1. Wyss S, Deb A, Watson R, Hammer S. Radiographic measurements for PDD diagnosis in Spix’s macaws (Cyanopsitta spixii) at Al Wabra Wildlife Preservation (AWWP), Qatar. In: Proceedings of the International Conference on Diseases of Zoo and Wild Animals. Zurich: University of Zurich; 2009. p. 349–54. 2. Lierz M, Herden C, Herzog S, Piepenbring A. Proventricular dilatation disease and avian borna...
متن کاملThe diagnosis of proventricular dilatation disease: use of a Western blot assay to detect antibodies against avian Borna virus.
Avian Borna virus (ABV) has recently been shown to be the causal agent of proventricular dilatation disease (PDD) a lethal neurologic disease of captive psittacines and other birds. An immunoblot assay was used to detect the presence of antibodies against avian Borna virus in the serum of affected birds. A lysate from ABV-infected duck embryo fibroblasts served as a source of antigen. The assay...
متن کاملAvian Bornavirus in Free-Ranging Psittacine Birds, Brazil
Avian bornavirus (ABV) has been identified as the cause of proventricular dilatation disease in birds, but the virus is also found in healthy birds. Most studies of ABV have focused on captive birds. We investigated 86 free-ranging psittacine birds in Brazil and found evidence for natural, long-term ABV infection.
متن کاملAvian Bornaviruses in Psittacine Birds from Europe and Australia with Proventricular Dilatation Disease
To determine whether avian bornaviruses (ABVs) were a factor in proventricular dilatation disease (PDD), we used immunohistochemistry, reverse transcription-PCR, and nucleotide sequence analysis to examine paraffin wax-embedded or frozen tissue samples of 31 psittacine birds with this disease. PDD is a fatal disease of psittacine birds associated with nonsuppurative encephalitis and ganglioneur...
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عنوان ژورنال:
- Emerging Infectious Diseases
دوره 14 شماره
صفحات -
تاریخ انتشار 2008